IndraLab

Statements

OTUD7B activates DNA-templated transcription. 3 / 3
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"Surprisingly, as a compensatory mechanism of PI3P generation, PIK3C2A was shown to be upregulated by Cezanne by promoting its transcription in a POLR2A-dependent way."
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"Consistently, the loss of Otud7b inhibited the activation of three major downstream transcription factors involved in T cell activation, NF-kappaB, NF-AT, and AP1 (XREF_FIG)."
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"USP39 suppressed the transcription activity of ETS2 by approximately 72.8%, while OTUD7A and OTUD7B increased the transcription activity of ETS2 by approximately 55.2% and 68.5%, respectively."
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