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USP18 binds ISG15 and STAT2. 1 / 1

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"The I60N mutation has been shown to disrupt USP18-ISG15-STAT2 protein-protein interactions required for scaffold function in humans.17 50 51 To help clarify the structural basis of these changes, we modeled the USP18-ISG15-STAT2 complex with AlphaFold."

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IndraLab

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USP18 binds ISG15 and STAT2. 1 / 1

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