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KCNQ1 activates CTNNB1. 2 / 2

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"The KCNQ1 ion channel inhibitor chromanol 293B caused membrane depolarization, redistribution of beta-catenin into the cytosol, and a reduced transepithelial electrical resistance, and stimulated CRC cell proliferation."

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reach

"Inhibition of KCNQ1 and the subsequent depolarization of the membrane inhibits β-catenin from localizing to the cell membrane attenuating Wnt/β-catenin signaling (Rapetti-Mauss et al., 2017; Rapetti-Mauss et al., 2020) ."

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IndraLab

Statements

KCNQ1 activates CTNNB1. 2 / 2

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