IndraLab

Statements

USP4 activates cell differentiation. 2 / 2
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"19 A recent study has demonstrated that USP4 could promote osteoblast differentiation via Activation of Wnt and beta-catenin signalling by inducing Runx2."
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"Conversely, deubiquitination of the K48 linked polyubiquitination of RORgammat by the deubiquitinase ubiquitinspecific protease USP4 stabilizes RORgammat and promotes its activation of Th17 associated genes, whereas inhibition of USP4 activity diminishes Th17 differentiation."
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