IndraLab

Statements

2,4,6-trinitrobenzenesulfonic acid inhibits NLRP3. 3 / 3
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"In addition, the TNBS-induced C57BL/6 mice model of colitis presented decreased c-Casp3, BAX/BCL-2, c-Casp9, NLRP3, ASC, c-Casp1, GSDMD, IL-18, high mobility group box 1 (HMGB1), NF-κB, ERK, p38, and JNK."
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"In addition, the TNBS-induced Sprague-Dawley mice model of colitis presented decreased IL-1β, IL-6, IL-12, caspase-1, caspase-3, TXNIP, and NLRP3 levels."
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"Norisoboldine, a natural aryl hydrocarbon receptor agonist, alleviates TNBS induced colitis in mice, by inhibiting the activation of NLRP3 inflammasome."
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