IndraLab

Statements

USP9X affects USP7
2 | 1 11
USP7 binds USP9X. 9 / 9
2 | 1 6
sparser
"FAM188B binds to USP7 and destabilizes the USP7-p53 interaction, thereby promoting p53 ubiquitination and degradation ( xref (iv))."
35008383
sparser
"By systematically analyzing, Yu Zhao et al. demonstrated that the OTUD4 could complex with USP7-USP9X. They proved that the OTUD4-USP7-USP9X complex was required for alkylation damage resistance and repair via promoting stability of ALKBH3, a demethylases for alkylation damage repair [ xref ]."
31011293
biogrid
No evidence text available
35926709
biogrid
No evidence text available
30224337
sparser
"To achieve this, the 181–550 region of OTUD4, which does not include the OTU catalytic domain, forms a complex with USP7 and USP9X. These two enzymes remove the K48-linked ubiquitin chains of ALKBH2 and ALKBH3 by their DUB activity, thereby preventing their degradation by the proteasome ( xref )."
38455765
sparser
"In our study, however, the amount of FAM188B-bound USP7 dramatically increased upon FAM188B overexpression in HCT-116 cells."
29795372
sparser
"The specificity of the USP9X and USP7 interaction was examined using unrelated DUBs, including USP4 ( xref ) and USP8 (data not shown), neither of which affected MARCH7 levels."
18410486
sparser
"Conversely, USP7 interacts with FAM188B and enhances tumor growth and survival of colon cancer cells[ xref , xref ]."
38292842
reach
"Additionally, we conducted Co-IP experiments in NRK-52E cells to verify the binding situation, and the results demonstrated varying degrees of binding between Usp49, Stambp, Usp8, Usp9x, Usp33, Usp20, and Usp7 with TLR4."
38874156
MARCHF7 binds USP9X and USP7. 3 / 3
| 3
sparser
"The interactions between MARCH7 and USP9X or USP7 are clearly not dependent on MARCH7’s E3 ligase activity or the DUBs cysteine protease function."
18410486
sparser
"MARCH7 associates with the DUBs USP9X and USP7."
18410486
sparser
"The interactions between MARCH7 and USP9X and USP7 could be confirmed in standard immunoprecipitations for MARCH7-ZZ and MARCH7 WI-ZZ and subsequent immunoblotting for USP9X and USP7 ( xref )."
18410486
USP7 binds USP39, USP10, USP9X, and FOXA1. 1 / 1
| 1
sparser
"To identify potential enzymes that could deubiquitinate FOXA1, we performed mass spectrometry analysis of FOXA1-associated proteins in LNCaP cells, which revealed multiple deubiquitinases, including USP7, USP39, USP10, and USP9X, that interact with FOXA1 (fig."
33827814
ALKBH3 binds USP7, USP9X, and OTUB1. 1 / 1
| 1
sparser
"Characterization of ALKBH3-interacting proteins show that USP7 and USP9x associate with another DUB OTU deubiquitinase 4 (OTUD4) to form a protein complex that deubiquitinates ALKBH3 [ xref ]."
30831436
ALKBH3 affects USP9X
| 1
ALKBH3 binds USP7, USP9X, and OTUB1. 1 / 1
| 1
sparser
"Characterization of ALKBH3-interacting proteins show that USP7 and USP9x associate with another DUB OTU deubiquitinase 4 (OTUD4) to form a protein complex that deubiquitinates ALKBH3 [ xref ]."
30831436