IndraLab

Statements


PTPN23 binds USP8.
1 | 2 2
1 | 2

reach
"We investigated in more detail how UBPY bound HD-PTP Bro1-V."

reach
"Hence, like STAM2, UBPY may bind HD-PTP at multiple sites."
| 1

sparser
"Altogether, these data indicate that CHMP4B binds the MIT domain of UBPY and the HD-PTP Bro1 domain simultaneously, though it is formally possible that CHMP4B additionally activates UBPY MIT to bind H[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
| 1

sparser
"Hence, like STAM2, UBPY may bind HD-PTP at multiple sites."
PTPN23 inhibits USP8.
| 1
PTPN23 inhibits USP8. 1 / 1
| 1

reach
"Indeed, depleting HD-PTP prevented endogenous UBPY from associating with EGFR, consistent with increased EGFR ubiquitination."