IndraLab

Statements


EIF3H affects EIF3F
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13 | 3 8

sparser
"In vitro GST-pulldown experiments confirmed that DTrc8 specifically interacted with eIF3f and eIF3h in addition to Csn5 ( xref )."

sparser
"In fact, interactions between DTrc8 and eIF3f or eIF3h were stronger than observed with Csn5."

sparser
"Moreover, both eIF3f and eIF3h interact directly with each other, supporting a possible scaffolding role for these subunits ( xref )."

sparser
"xDnd1 directly binds eIF3f and in IP experiments, brings down eIF3m and eIF3h, which associate with eIF3f ( xref )."

sparser
"Our results show that At eIF3f interacts with eIF3h."

sparser
"In contrast, mammalian eIF3f interacts with eIF3h directly, and seems not indispensable for other eIF3 subunits assembly, based on previous reports ( xref ; xref )."

reach
"Meanwhile, knockdown EIF3F, which directly binds to EIF3H and could function as deubiquitinase, has no effect on YAP expression and cytosol and nuclear ratios (XREF_FIG - XREF_FIG and XREF_SUPPLEMENTARY)."

reach
"Based on the convincing fit of the eIF3a and eIF3c structure into the EM density, we attempted to dock the recently solved paralogs of eIF3e (CSN1) and the eIF3h and eIF3f heterodimer (Rpn8 and Rpn11) into the eIF3.IRES EM density along with older models for eIF3k, eIF3m, and eIF3l (XREF_FIG A)."

sparser
"To test whether eIF3f and eIF3h actually interact with the eIF4GI682-1130-MS2 fusion protein, we co-expressed both factors transiently in HEK 293T cells, immunoprecipitated the eIF4G core domain via its MS2 fusion in presence of RNase A and tested for its association of eIF3f and eIF3h ( xref )."

sparser
"Meanwhile, knockdown EIF3F, which directly binds to EIF3H and could function as deubiquitinase, has no effect on YAP expression and cytosol/nuclear ratios ( xref – xref and xref )."
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sparser
"A polysome mRNA analysis on HeLa, HEK293 and NIH3T3 cells has revealed that eIF3e, eIF3f and eIF3h mRNAs are mainly associated with subpolysomal particles in quiescent or growth-arrested cells, but mostly associated with polysomes in growing cells [ xref ]."

sparser
"We also demonstrated that At eIF3f interacts with Arabidopsis eIF3e and eIF3h."

sparser
"Co‐expression of these bait and target constructs showed that At eIF3f interacts with Arabidopsis eIF3e and eIF3h in yeast ( xref )."

sparser
"This result shows that At eIF3f interacts with eIF3e and eIF3h in plant cells."

sparser
"In this study, we demonstrated that At eIF3f interacts with both Arabidopsis eIF3e and eIF3h in Y2H and BiFC assays."
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sparser
"Here, we demonstrate that Drosophila and human TRC8 proteins also interact with eIF3f and eIF3h ( xref )."

sparser
"The subunit eIF3g interacts with Paip1, a Poly (A)-binding protein and stimulates translation initiation [ xref ], whereas the subunits eIF3h and eIF3f interact with TRC8, a ubiquitin E3 ligase, and inhibit protein synthesis, possibly through ubiquitilation of eIF3 or some other translational components [ xref ]."
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sparser
"In both the CGGA and TCGA datasets, the expression levels of eIF3d, eIF3e, eIF3f, eIF3h and eIF3l highly were associated with the IDH mutant status of gliomas."
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sparser
"The same study however also suggests a close association of eIF3f and eIF3h (among other subunits) with eIF4GI."
EIF3A affects EIF3D, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, and EIF3K
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sparser
"In , it has also been shown that eIF3a interacts with eIF3d, eIF3f, eIF3g, eIF3h , eIF3i , eIF3j and eIF3k ."