IndraLab

Statements

AMOT binds USP17L2. 5 / 5
| 4 1
reach
"These data provide evidence that DUB3 interacts with AMOT and LATS2 proteins and regulates their turnover."
28061504
reach
"The purpose of the seemingly contradictory function of DUB3 with respect to ITCH in this setting remains elusive but it is feasible that DUB3 binding to the AMOT and LATS complex may be regulated by p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28923280
reach
"Interestingly DUB3 also interacts with and deubiquitinates AMOT, AMOTL1, and the kinases LATS1 and LATS2 to promote their stability and in so doing decrease YAP activity [124]."
28923280
sparser
"Although DUB3 also stabilizes the E3 ligase ITCH, interaction of DUB3 with LATS1/2 and AMOT in this complex is hypothesized to offset the effects of increased ITCH activity toward these substrates."
28061504
reach
"Although DUB3 also stabilizes the E3 ligase ITCH, interaction of DUB3 with LATS1/2 and AMOT in this complex is hypothesized to offset the effects of increased ITCH activity toward these substrates."
28061504