IndraLab

Statements


TGFB1 leads to the phosphorylation of SRC on Y419. 4 / 4
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reach
"TGF-beta1 stimulation of quiescent VSMC results in phosphorylation (at Y416) of the non receptor tyrosine kinase pp60 c- src and the rapid activation of the epidermal growth factor receptor (EGFR) atY845 (a src-target residue)."

sparser
"VSMC pretreatment with the src kinase-specific inhibitor SU6656, as expected, prevented the TGF-β1-dependent increase in c- Src Y416 phosphorylation ( xref )."

reach
"As shown in XREF_FIG, TGF-beta1 induced the phosphorylation of FAK (Y925), Src (Y416), and paxillin (Y118), and these phosphorylation events were inhibited by KY-05009."

reach
"Both hypotonicity and TGF beta1 treatment increased phosphorylation of Src Tyr416 but did not effect Src kinase expression."