IndraLab

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K66R be key ubiquitination site K48-linked poly-ubiquitination inhibits OTULIN. 1 / 1
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eidos
"Single-mutant variants displayed a significant reduction in ubiquitination compared to wild-type OTULIN ( Fig. 9f ) , implying that K66R might be a key ubiquitination site for K48-linked poly-ubiquitination which could lead to OTULIN degradation ."