IndraLab

Statements

CHMP3 inhibits KCNH2. 2 / 2
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"Consistently, overexpression of the endosomal deubiquitinating enzyme signal transducing adaptor molecule binding protein significantly accelerated whereas knockdown of endogenous signal transducing adaptor molecule binding protein impeded degradation of the mature hERG channels under low K (+) conditions."
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"Overexpression of Vps24 protein, also known as charged multivesicular body protein 3, significantly accelerated degradation of mature hERG channels, whereas knockdown of Vps24 impeded this process."
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