IndraLab

Statements

EIF3F activates Notch. 3 / 3
1 | 2
reach
"These results suggest that eIF3f is specifically involved in an ubiquitination and deubiquitination process targeting activated Notch."
21124883
reach
"The translation initiation factor 3f (EIF3F) is recruited to activate Notch on endocytic vesicles by the Deltex1 serving as a bridging factor."
28031783
signor
"The activated form of notch needs to be deubiquitinated before being processed by the gamma-secretase activity and entering the nucleus, where it fulfills its transcriptional function. The enzyme accounting for this deubiquitinase activity is eif3f, known so far as a translation initiation factor."
21124883