IndraLab

Statements

NOP53 inhibits USP15. 3 / 3
| 3
reach
"It appeared that GLTSCR2 supported and inhibited the ability of USP15, respectively, to remove K63 linked and K48 linked ubiquitination of RIG-I."
27824081
reach
"Interestingly, we detected that reduction of endogenous GLTSCR2 resulted in increased USP15 activity in removing K48 linked ubiquitination of RIG-I-N in GLTSCR2 knockdown cells (XREF_FIG, lane 6), whereas GLTSCR2 presence reduced the activity of USP15 in removing K48 linked ubiquitination of RIG-I-N in HEK293T cells (lane 3)."
27824081
reach
"Interestingly, we detected that reduction of endogenous GLTSCR2 resulted in increased USP15 activity in removing K48-linked ubiquitination of RIG-I-N in GLTSCR2 knockdown cells (Fig. 6d, lane 6) , whereas GLTSCR2 presence reduced the activity of USP15 in removing K48-linked ubiquitination of RIG-I-N in HEK293T cells (lane 3)."
27824081