IndraLab

Statements

CYLD binds Tax. 16 / 16
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reach
"Interestingly, the Tax and CYLD interaction appeared to be enhanced by the IKK regulatory subunit, IKKgamma, which is known to interact with both Tax [XREF_BIBR - XREF_BIBR] and CYLD [XREF_BIBR, XREF_BIBR]."
21824392
reach
"We first examined the potential physical interaction between Tax and CYLD."
21824392
sparser
"Acting in opposition to Tax ubiquitination, the deubiquitinase CYLD interacts with Tax and removes ubiquitin moieties thereby reducing the association of Tax with IKK."
23226145
reach
"We show here that the deubiquitinase CYLD physically interacts with Tax and negatively regulates the ubiquitination of this viral protein."
21824392
sparser
"We show here that the deubiquitinase CYLD physically interacts with Tax and negatively regulates the ubiquitination of this viral protein."
21824392
sparser
"In the present study, we have shown that Tax forms a complex with CYLD, in which CYLD strongly inhibits the ubiquitination and signaling function of Tax."
21824392
reach
"A recent study showed that CYLD, a DUB and tumor suppressor involved in NF-kappaB signaling pathways, interacts with Tax and removes ubiquitin chains that results in impaired Tax interaction with NEMO [XREF_BIBR]."
25341660
sparser
"Interestingly, the Tax/CYLD interaction appeared to be enhanced by the IKK regulatory subunit, IKKγ, which is known to interact with both Tax [ xref - xref ] and CYLD [ xref , xref ]."
21824392
sparser
"We found that Tax interacts with CYLD, a deubiquitinase that negatively regulates NF-κB activity, by inactivating it ( xref )."
22865346
reach
"Furthermore, Tax also interacted with CYLD in transiently transfected cells."
21824392
sparser
"Furthermore, Tax also interacted with CYLD in transiently transfected cells (Figure xref )."
21824392
sparser
"CYLD is physically assembled into the Tax complex and involved in negative regulation of Tax ubiquitination and signaling function."
21824392
reach
"In the present study, we have shown that Tax forms a complex with CYLD, in which CYLD strongly inhibits the ubiquitination and signaling function of Tax."
21824392
sparser
"Tax physically interacts with CYLD."
21824392
reach
"Tax physically interacts with CYLD."
21824392
reach
"We found that Tax interacts with CYLD, a deubiquitinase that negatively regulates NF-kappaB activity, by inactivating it."
22865346