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Modified CDC20 decreases the amount of USP22. 1 / 1
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"We noticed that the expression of CDC20, but not CDH1 or FBW7, significantly inhibited USP22 protein expression (XREF_FIG), implying the CDC20 containing APC/C E3 ligase complex is involved in regulating USP22 protein stability in HCT116 cells, in particular during the transition period from M to G0 phase during cell cycle progression."