The INDRA Database

sparser

"Whether the YOD1-Hrd1 interaction reflects a direct interaction or an interaction mediated by Hrd1 adaptors is unknown."

24068323

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sparser

"When FLAG-WT and C160S YOD1 were precipitated from cells under a native condition and the precipitated material probed with antibodies against these membrane proteins, endogenous Hrd1 consistently bound to C160S YOD1 with higher affinity than WT YOD1 ( xref , first panel, compare lane 6 with lane 5; quantified in graph on right)."

24068323

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biogrid

No evidence text available

24068323

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reach

"WT Hrd1-Myc coprecipitated with FLAG-WT YOD1 only when FLAG-WT YOD1was expressed in cells (XREF_FIG, top and second panels, compare lane 2 with lane 1), indicating that Hrd1 binds to YOD1."

24068323

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sparser

"This finding indicates that gp78 does not engage YOD1, and demonstrates specificity of the YOD1-Hrd1 interaction."

24068323

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sparser

"Both WT Hrd1-Myc and cyt Hrd1-Myc but not TM1-6 Hrd1-Myc coprecipitated with FLAG-WT YOD1 ( xref , top three panels, compare lanes 1 and 2 with lane 3), demonstrating that Hrd1’s cytosolic domain interacts with YOD1."

24068323

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reach

"Our coimmunoprecipitation experiments revealed that YOD1 binds to Hrd1 via Hrd1 's cytosolic domain."

24068323

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sparser

"WT Hrd1-Myc coprecipitated with FLAG-WT YOD1 only when FLAG-WT YOD1was expressed in cells ( xref , top and second panels, compare lane 2 with lane 1), indicating that Hrd1 binds to YOD1."

24068323

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sparser

"Our coimmunoprecipitation experiments revealed that YOD1 binds to Hrd1 via Hrd1’s cytosolic domain."

24068323

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reach

"YOD1 can bind to HRD1, and HRD1 as an ER associated E3 is crucial in the process of reverse transport."

33546413

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reach

"We first tested a potential interaction between YOD1 and Hrd1."