IndraLab

Statements


APC/C Cdh1 activates USP1. 3 / 3
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"We show that during G1, USP1 is targeted for degradation by APC/C Cdh1 to ensure that USP1 levels are kept in check before S phase entry."

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"Here, we show that USP1 can be targeted for degradation by the APC/C Cdh1 cell cycle regulator."

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"We have shown that the APC/C Cdh1 E3 Ub ligase targets Usp1 for the proteasome mediated degradation in the G1 phase of the cell cycle."