IndraLab

Statements

KCN binds KCNQ1. 5 / 6
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sparser
"In a heterozygote, wild type and defective monomers can co-assemble to form an impaired KCNQ1 potassium channel complex, which can result in a prolonged QT interval ( xref ; xref )."
30461122
sparser
"We also observed drastic reductions in Kcne1 and Kcne2 expression, which is not surprising because KCNE1 and KCNE2 subunits form potassium channel complexes with KCNQ1 that are important for K + secretion and production of inner ear endolymph."
31550482
sparser
"MinK is a potassium channel subunit which co-assembles with KvLQT1 to form the slowly activated, delayed rectifier K current that plays an important role in cardiac depolarization( xref ; xref )."
25442735
sparser
"CALM1 is responsible for the mediation of L-type calcium channel depending on voltage [28], regulation of CACNA1C inactivation depending on calcium [29], positive regulation of KCNN2's potassium channel activity activated by calcium [30], formation of the KCNQ1-based potassium channel complex, and regulation of channel electrophysiological activities by binding to calcium [31]."
34899951
sparser
"CALM1 is responsible for the mediation of L-type calcium channel depending on voltage [ xref ], regulation of CACNA1C inactivation depending on calcium [ xref ], positive regulation of KCNN2's potassium channel activity activated by calcium [ xref ], formation of the KCNQ1-based potassium channel complex, and regulation of channel electrophysiological activities by binding to calcium [ xref ]."
34899951