IndraLab

Statements

Cyclosporin A inhibits ITCH. 5 / 5
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"Intraperitoneal injection of cyclosporine A dose-dependently inhibited increased itch related receptor gene expression, such as interleukin-31 receptor A and neurokinin-1 receptor, in the dorsal root ganglion of atopic dermatitis model mice."
26671728
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"A case series from Hong Kong [XREF_BIBR] comprising 14 children with AC, VKC, AKC with mean age 10.8 +/- 3.2 years showed that topical CsA 0.05% Restasis reduced symptoms, signs, and itch severity scores compared with baseline (p < = 0.001) and 78.6% of subjects successfully tapered off steroid eye drops."
28487836
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"By using this system we have found that itch in atopic dermatitis is not inhibited by antihistamines but by cyclosporin A, a drug inhibiting cytokine production."
1419979
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"Cyclosporin A significantly reduced the itch intensity, the eczema score and the consumption of topical hydrocortisone."
1977258
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"Supporting this theory is the finding that ciclosporin A, an inhibitor of lymphokine production, reduces itch in atopic dermatitis."
1575979