IndraLab

Statements

NLRP3 binds USP30. 3 / 3
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sparser
"The interaction between USP30 and NLRP3 was verified by co-immunoprecipitation and ubiquitination assays."
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reach
"The interaction between USP30 and NLRP3 was verified by co-immunoprecipitation and ubiquitination assays."
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sparser
"Finally, we show that inhibition of USP30 via MF-094 treatment facilitated wound healing in diabetic rats and resulted in decreased protein levels of NLRP3 and its downstream target caspase-1 p20, thus establishing the physiological importance of the identified USP30-NLRP3 link."
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