IndraLab

Statements

IKK_complex inhibits CYLD. 5 / 5
| 4 1
reach
"On the contrary, ectopic expression of IKK significantly reduced CYLD protein abundance in 293T cells ectopically expressing HA tagged CYLD."
24961988
reach
"IKK blockade reactivates CYLD, as evidenced by the reduction in RIPK1 ubiquitination, which leads to the association of RIPK1 with the death inducing signaling complex (DISC) to trigger cell death."
32024820
reach
"IKK blockade reactivated CYLD, as evidenced by the reduction in RIPK1 ubiquitination, which led to the association of RIPK1 with the DISC, triggering cell death."
32024820
reach
"IKK blockade reactivates CYLD, as evidenced by the reduction in RIPK1 ubiquitination, which leads to the association of RIPK1 with the death-inducing signaling complex (DISC) to trigger cell death."
32024820
sparser
"Reiley et al have shown that NEMO is required for the IKK complex to phosphorylate and inhibit the deubiquitinase CYLD [ xref ], a critical component of the necrotic machinery [ xref ], as can the TNF-inducible IKKε [ xref ]."
21232018