IndraLab

Statements


Mutated SCN5A inhibits NAV1. 2 / 2
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"Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels."

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"SCN5A mutations can impair the function of Nav1.5 and induce various arrhythmias [XREF_BIBR]."