IndraLab

Statements

PCBP1 binds KCNF1. 5 / 5
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sparser
"Both truncated PCBP1-KH1 and hnRNPK-KH3 can bind C-rich DNA independently [ xref , xref ]."
41614300
sparser
"Our results revealed that break of PCBP1 KH1 domain apparently mitigated p27 protein expression and the reporter activity, but not the KH2 and KH3 mutations, indicating that PCBP1 binds to p27 mRNA mainly through its KH1 domain, rather than KH2 and KH3 domains, which is consistent to that PCBP1 KH1 domain interacts with stem-loops I and IV of EV71 5’UTR, facilitating viral replication [ xref ]."
30086790
sparser
"We first constructed and purified two protein probes: one containing the PCBP1-KH1 domain (designated C1) and the other containing the hnRNPK-KH3 domain (designated K3), each fused at the C-terminus with a V5 tag (Fig.  xref and xref )."
41614300
sparser
"Thus, we proposed that KH1 domain of PCBP1 specifically binds to stem-loop I and IV of EV71 5′UTR, which may play an important biological function in viral replication."
24489926
sparser
"The hnRNP K specifically binds to DICE by KH3, whereas PCBP1 binds by KH1 and KH3 ( xref )."
36452487