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Small molecule b-AP15 inhibits UCHL5. 2 / 2

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"The small molecule b-AP15 as a previously unidentified class of proteasome inhibitor abrogates the activity of two 19S regulatory-particle-associated deubiquitinases, UCH37 and UCHL5, and USP14."

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"To investigate the role of proteasomal deubiquitinases in HNSCC, we studied the effects of the small molecule b-AP15, which inhibits both USP14 and UCHL5 [39]."

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Small molecule b-AP15 inhibits UCHL5. 2 / 2

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