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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SOS1 binds CBL, ATP6AP2, and GRB2. 2 / 2

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"These observations fit well with previous studies showing that SOS1 peptides bind to individual SH3 domains from GRB2 with affinities ranging from 20μM to 1mM , while the affinity for the binding of f[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"These observations fit well with previous studies showing that SOS1 peptides bind to individual SH3 domains from GRB2 with affinities ranging from 20 µM to 1 mM [ xref – xref ], while the affinity for the binding of full-length GRB2 with full-length SOS1 or the complete PRR of SOS1 and CBL is between 300 and 400 nM ( xref ) and [ xref – xref ]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...