IndraLab

Statements



reach
"More importantly, USP11 could promote cell growth and metastasis in colorectal cancer [XREF_BIBR, XREF_BIBR]."

reach
"For example, the aberrant expression of USP11 was found to interact with nuclear factor 90 and promote its deubiquitination, to promote the proliferation and metastasis of hepatocellular carcinoma."

reach
"USP11 promoted tumor growth and metastasis in CRC via the ERK and MAPK pathway by stabilizing PPP1CA, suggesting USP11 is a potential prognostic marker."

reach
"Namely, USP11 has been shown to promote the proliferation and metastasis of hepatocellular carcinoma (HCC), but the underlying molecular basis is poorly understood."

reach
"Overall, we suggest that USP11 promotes HCC cell metastasis, and we provide the first evidence of the prognostic significance of USP11 expression in HCC, which suggests that USP11 is a promising therapeutic target for the treatment of HCC."

reach
"Taken together, these results indicate that the E2F1 and USP11 signal axis promotes HCC proliferation and metastasis and inhibits autophagy, which provides an experimental basis for the treatment of HCC."

reach
"Additionally, USP11 could promote cell proliferation and metastasis via regulating nuclear factor 90 (NF90) in hepatocellular carcinoma [XREF_BIBR]."

reach
"USP11 promotes colorectal cancer growth and metastasis by stabilizing PPP1CA, activating the ERK/MAPK pathway, and insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) signaling (151), and interacting with nuclear factor 90 (NF90) to promote HCC proliferation and metastasis (152)."

reach
"The E2F1 and USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK and mTOR pathway."

eidos
"Additionally , USP11 could promote cell proliferation and metastasis via regulating nuclear factor 90 ( NF90 ) in hepatocellular carcinoma [ 37 ] ."

reach
"USP11 promotes growth and metastasis of colorectal cancer via PPP1CA mediated activation of ERK and MAPK signaling pathway."