IndraLab

Statements

SQSTM1 binds TRAF6 and CYLD. 8 / 8
| 8
sparser
"Sal A Restrains Angiogenesis by Promoting P62-CYLD-TRAF6 Interactions."
29081889
sparser
"Co-IP results in our study presented that Sal A remarkably promotes P62-CYLD-TRAF6 interaction."
29081889
sparser
"Coimmunoprecipitation result (Figures xref – xref ) reveals apparent P62-CYLD-TRAF6 interaction in the Sal A + OX-LDL group than that in the OX-LDL group."
29081889
sparser
"Sal A antagonized OX-LDL effects and restrained CNV progression by decreasing VEGF/PDGF/CYLD, increasing antiangiostatin levels, and promoting P62-CYLD-TRAF6 interaction."
29081889
sparser
"Thus, CYLD appears to play dual roles in angiogenesis pathology: facilitating tube formation and promoting VEGF expression, meanwhile negatively regulating TRAF6 function via P62-CYLD-TRAF6 interaction."
29081889
sparser
"Given that this was seen within 1–2 h after stimulation, much earlier than increased p62 expression, the ordered interaction of p62 with TRAF6 and CYLD during macrophage activation is not likely to be entirely attributed to inducible p62 expression, but may involve posttrans-lational modification of p62, such as ubiquitination ( xref ) and phosphorylation ( xref )."
19201866
sparser
"What we found in macrophages was a time-dependent, ordered interaction of p62 with TRAF6 and CYLD."
19201866
sparser
"We also demonstrated that Sal A modulates angiogenesis process by decreasing CYLD level and promoting P62-CYLD-TRAF6 interaction."
29081889