IndraLab

Statements

HLA-B binds KCNH2. 2 / 2
| 2
sparser
"Although the molecular mechanisms linking AP to QT prolongation have not been fully elucidated yet, there is evidence pointing to a direct effect on certain subtypes of myocardial ion channels, particularly the human ether-a-go-go-related gene (HERG) that encodes for a protein associated with a cardiac K + channel involved in regulating repolarizing currents [ xref – xref ]."
28359306
sparser
"Eight well-known PKC selective peptidomimmetics and general synthetic modulators were used to modulate the protein-protein interactions between hERG and the major PKC subtypes."
24464434