OTUB1 leads to the deubiquitination of UBE2N. 2 / 2
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"Since, OTUB1 inhibits UBC13 dependent polyubiquitylation but not monoubiquitylation, it may be that a single ubiquitin conjugated to another protein at DSBs is sufficient to be recognized by the MIU d[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

"Although OTUB1 is not catalytically involved in deubiquitinating these K63-linked chains, it may interact with Ubc13 and inhibit the E3 ligase RNF168"