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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

NSC112200 inhibits ZRANB1. 2 / 2

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"We also found that NSC112200 inhibited the deubiquitinase activity of ZRANB1, but not another OTU family member, A20 (XREF_SUPPLEMENTARY)."

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"In an in vitro deubiquitination assay using ubiquitin chains as substrates, we found that ZRANB1 cleaved K33 linked di-ubiquitin; this cleavage was blocked by NSC112200, but not by the control compound NSC60650 (1,5-dichloro-2,4-dihydroxybenzene) (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...