IndraLab

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HIF1A activates USP28. 2 / 2
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reach
"Here, we report that USP28 is a SUMOylated protein in normoxia with moderate deubiquitinating activity towards HIF-1alpha in vitro, while hypoxia and HIF-1alpha activate USP28 through SENP1 mediated USP28 deSUMOylation to further accumulate HIF-1alpha protein in cells."
30622440
sparser
"Here, we report that USP28 is a SUMOylated protein in normoxia with moderate deubiquitinating activity towards HIF-1α in vitro, while hypoxia and HIF-1α activate USP28 through SENP1-mediated USP28 deSUMOylation to further accumulate HIF-1α protein in cells."
30622440