IndraLab

Statements

STAMBP activates Ubiquitin. 3 / 3
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reach
"For the AMSH treatment, substrates were modified with 400 muM wild-type ubiquitin, then treated with 20 muM AMSH for 30 minutes at RT before analysis by SDS-PAGE and visualization by 5-FAM fluorescence on a ChemiDoc (Bio-Rad)."
30929903
reach
"71 In contrast to PAR2, USP8 (or AMSH) does not impact CXCR4 ubiquitination but instead modulates the ubiquitin status of ESCRT-0 that is ubiquitinated by the E3 ligase AIP4, 23 reinforcing the idea that ubiquitination of the transport machinery represents an important regulatory event in GPCR trafficking."
26055053
reach
"Similarly, endosomal deubiquitinase AMSH (Associated Molecule with the SH3-domain of STAM) has been shown to antagonize the ubiquitin dependent lysosomal degradation of EGFR by trimming the K63 linked ubiquitin chains [XREF_BIBR] while other studies have shown this DUB to be required for MVB dependent EGFR degradation [XREF_BIBR, XREF_BIBR]."
23085373