IndraLab

Statements

ZUP1 inhibits CRC growth. 6 / 6
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"Therefore, DUb may inhibit CRC growth by affecting the metabolism of colorectal cancer.Taken together, as an important finding of the current study, DUb is determined to suppress CRC growth in xenograft mouse models with CRC CT26 cells and human CRC tissues."
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"Our results show that DUb markedly suppresses CRC growth in xenograft mouse models with colorectal carcinoma CT26 cells and human-derived xenograft tumor."
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"DUb was found to significantly attenuate CRC growth (Figure 1A) and weight (Figure 1B)."
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"Scale bar = 50 µm in C. **p < 0.01.FIGURE 2: DUb inhibits the CRC growth in the patient-derived xenograft (PDX) tumor models."
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"These results shows that DUb reduces the migratory and invasive abilities of CRC cell.To determine the mechanism of DUb inhibiting CRC growth, a qRT-PCR array was performed."
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"Our results in this study demonstrates that DUb may be the potential agent for the treatment of CRC through upregulating SIRT2.FIGURE 1: DUb inhibits CRC growth in CT26 xenograft tumor models."
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