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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CHUK binds IKBKB, IKBKG, and KCNG1. 2 / 2

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"We next examined if recruitment of IKK1 and IKK2 to the K13-NEMO complex is also associated with “T Loop” phosphorylation of IKK1, IKK2 or both."

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"As shown in xref , while interaction of K13 with NEMO, IKK1, and IKK2 was readily detected in samples immunoprecipitated with Flag antibody from wild-type Jurkat cells, no significant interaction between K13 and IKK1 or IKK2 was observed in the NEMO-deficient Jurkat cells, Stimulation of cells with TNFα or IL-1 induces recruitment of IKK1 and IKK2 to NEMO and their subsequent phosphorylation and activation xref , xref ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...