IndraLab

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BDNF methylates BDNF. 5 / 5
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"The underlying mechanisms concerning BDNF signaling and DNA methylation of Bdnf were also explored."
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"We hypothesized that prenatal exposure to ambient PAH in mice would be associated with impaired neurocognition, increased anxiety, altered cortical expression of Bdnf and Grin2b , and greater DNA methylation of Bdnf ."
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"Increased Methylation of Brain-Derived Neurotrophic Factor (BDNF) Is Related to Emotionally Unstable Personality Disorder and Severity of Suicide Attempt in Women."
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"Analyses of Nr3c1and Bdnf (IV and IX) CpG methylation indicated increased hippocampal Nr3c1 methylation in maternally separated C57BL/6J males and increased hippocampal Bdnf IX methylation in male and female maternally separated Balb/c mice."
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"The 5-AzaD treatments also elevated BDNF at the mRNA (p<0.01) and protein (Low-n-3/WD/5-AzaD Vs Low-n-3/WD/VEH, p<0.05; xref ) levels, which corroborates the repressive action of Bdnf methylation on BDNF."
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