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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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AGT decreases the amount of SCN5A. 3 / 3

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"11 Ang II can also decrease SCN5A transcription and current through production of H 2 O 2 resulting in nuclear factor kappa B (NF-kappaB) binding to the sodium channel promoter."

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"Moreover, NF-kappaB has been implicated in the Ang II induced decrease of SCN5A transcription and sodium current."

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"In conclusion, ANG II can decrease scn5a transcription and current."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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AGT decreases the amount of SCN5A. 3 / 3

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