IndraLab

Statements

AMPK_alpha binds USP10 and PTEN. 3 / 3
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"Therefore, we conclude that USP10 interacts with PTEN and AMPKα, inhibits their polyubiquitylation, and as a result stabilizes PTEN and AMPKα."
30056112
sparser
"To further dissect how USP10 inhibits mTOR activity, we investigated whether the stabilization of PTEN [] and AMPKα [] by USP10 involved the physical interactions of USP10 with PTEN and AMPKα."
30056112
sparser
"Inversely, endogenous PTEN and AMPKα interacted with endogenous USP10 in HCC-LM3 and HUH7 cells (B)."
30056112