IndraLab

Statements

PRMT6 methylates CDKN2A. 4 / 4
| 2 2
sparser
"PRMT6 methylates p53, p21, and p16, involving in regulation of cell proliferation, cell-cycle arrest, senescence, and apoptosis [ xref , xref , xref ]."
33260152
sparser
"In addition to suppressing the expression of the cell cycle inhibitors p16 and p21 through epigenetic modifications [ xref , xref ], PRMT6 also methylates p16 and p21 and negatively regulates their functions."
| PMC
reach
"PRMT6 also directly methylates and inhibits the activity of tumor suppressor p16 (INK4A) [52]."
24742914
reach
"PRMT6 methylates p53, p21, and p16, involving in regulation of cell proliferation, cell-cycle arrest, senescence, and apoptosis [XREF_BIBR, XREF_BIBR, XREF_BIBR]."
33260152