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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Phosphorylated EGFR activates AKT. 2 / 2

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"who discovered that whilst chemically crosslinked cell surface EGFR dimers become phosphorylated and recruit the appropriate adapter proteins, in the absence of ligand these phosphorylated EGFR dimers[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The phosphorylated EGFR will then lead to the activation of the RAS-RAF-MAPK kinase and the PI3K-Akt transduction cascades."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...