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AKT phosphorylated on S473 activates MTOR. 2 / 2
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"The data demonstrated the activities on the Akt and mTOR signaling including the phosphorylation of Akt at both Thr308 and Ser473 residues in the activation loop and hydrophobic motif of the kinase, respectively, and phosphorylation of mTOR at Ser2448 that was dependent on the kinase activity [XREF_BIBR, XREF_BIBR]."
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"As a downstream effector of PI3K, phosphorylated Akt at Ser473 can activate mTOR at Ser2448, which is carried out by two distinct complexes: mTORC1 and mTORC2, and mTOR activation have been implicated[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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