IndraLab

Statements

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"We found that EIF3H overexpression significantly increased the abilities of migration and invasion in KYSE150 and KYSE510 cells."
32867821
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"Functional analyses showed that EIF3H overexpression promoted LUAD cell migration and invasion in vitro as well as metastasis in nude mice by activating epithelial-mesenchymal transition (EMT) signaling."
32064160
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"Increased expression of EIF3H gene increases CRC growth and invasiveness thereby providing a biological mechanism for the 8q23.3 association XREF_BIBR."
25609216
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"We found that EIF3H is significantly upregulated in esophageal cancer and ectopic expression of EIF3H in ESCC cell lines promotes cell proliferation, colony formation, migration and invasion."
32867821
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"We observed, while the elevation of EIF3H drastically increases the tumor invasion in various breast cancer cell lines, including MDA-MB-231, 4T1, depletion of EIF3H by RNA interference largely attenuates tumor invasion (XREF_FIG - XREF_FIG & XREF_SUPPLEMENTARY - XREF_SUPPLEMENTARY)."
32269044
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"As shown in XREF_FIG - XREF_FIG and XREF_SUPPLEMENTARY - XREF_SUPPLEMENTARY, knockdown of either the YAP and CTGF expression abrogated EIF3H driven tumor cell invasion."
32269044
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"We show that increased expression of EIF3H gene increases CRC growth and invasiveness thereby providing a biological mechanism for the 8q23.3 association."
20862326
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"To further determine whether YAP is a physiologically relevant substrate for EIF3H that mediates EIF3H promoted tumor cell invasion, we have characterized catalytic function for EIF3H in regulating YAP abundance, YAP turnover rate and YAP ubiquitylation."
32269044