IndraLab

Statements

CYLD binds TRAIP. 13 / 16
2 1 | 3 7
biogrid
No evidence text available
14676304
sparser
"An identical staining pattern was observed in cos-7 cells expressing either CYLD or TRIP, suggesting that CYLD–TRIP interaction does not change their subcellular localizations."
14676304
sparser
"Furthermore, only the central domain (aa 106–593) but neither N-(aa 1–132) nor C-(aa 558–956) terminal domains of CYLD interacted with full-length TRIP."
14676304
sparser
"To define more precisely the region of TRIP binding to CYLD, we constructed pGADT7 expression vectors for TRIP-N (aa 1–289) and TRIP-C (aa 290–469)."
14676304
biogrid
No evidence text available
14676304
sparser
"The implication of the interacting pair CYLD–TRIP in NF-κB signaling adds more players to the already highly complex regulation of NF-κB activity influencing proliferation and differentiation of epidermis and skin appendages."
14676304
sparser
"Another report demonstrated that the C-terminal domain of TRIP interacts with the tumor suppressor CYLD, but there was no evidence that full-length TRIP could bind CYLD [6] ."
17544371
hprd
No evidence text available
14676304
reach
"To define more precisely the region of TRIP binding to CYLD, we constructed pGADT7 expression vectors for TRIP-N (aa 1-289) and TRIP-C (aa 290-469)."
14676304
sparser
"This study confirmed the interaction of CYLD with the C-terminal domain of TRIP by far Western analysis and co-immunoprecipitations in mammalian cells."
18687060
sparser
"To confirm the CYLD–TRIP interaction in mammalian cells we performed Far Western analysis with GST-TRIP fusion proteins and cell extracts of 293T cells transfected with HA-tagged full-length CYLD."
14676304
reach
"CYLD and Syk, the two regulators of NF-kappaB signaling (Yamada et al., 2001; Brummelkamp et al., 2003; Kovalenko et al., 2003; Trompouki et al., 2003; Chung et al., 2007; Lim et al., 2007; Zhou and G[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21068752
reach
"The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor."
14676304