IndraLab

Statements



reach
"XREF_BIBR Tryptophan produced by the gut microbiome causes an itching sensation in the skin, XREF_BIBR whereas Lactobacillus species and Bifidobacterium species can produce gamma-aminobutyric acid (GABA), which inhibits skin itch."

reach
"XREF_BIBR Tryptophan produced by the gut microbiome causes an itching sensation in the skin, XREF_BIBR whereas Lactobacillus species and Bifidobacterium species can produce gamma-aminobutyric acid (GABA), which inhibits skin itch."

reach
"Scratch evoked inhibition was also significantly attenuated (but not abolished) by interruption of the upper cervical spinal cord, indicating the involvement of both segmental and suprasegmental circuits that engage glycine- and GABA mediated inhibition of spinal itch signaling neurons by noxious counterstimuli."

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"Together with the in situ hybridization data, these results suggest that GABA A Rs inhibit the spinal relay of itch signals primarily at the level of dorsal horn interneurons rather than via inhibition of primary pruritoceptors."