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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 decreases the amount of mycn. 2 / 2

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"Moreover, immunohistochemical staining revealed that N-Myc levels are reduced in the Hausp knockout tissues (XREF_FIG); notably, this effect on N-Myc protein levels caused by the Hausp knockout remained the same in the TP53-null background (XREF_FIG)."

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"As shown in XREF_FIG, reducing HAUSP (RNAi and HAUSP pool) decreased N-Myc protein levels; moreover, the levels of N-Myc were consistently decreased by using each of the four individual oligos composing the HAUSP RNAi pool, excluding off-target effects (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...