A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

Mutated TP53 decreases the amount of mutated TP53. 1 / 1
| 1
reach
"Given that depletion of mutant p53 and RUNX2 reduces the expression level of RUNX2 and mutant p53, respectively, it is likely that there exists a positive auto-regulatory feedback loop between mutant p53 and RUNX2, and this regulatory system might contribute to the low sensitivity of MiaPaCa-2 cells against SAHA."