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UCHL1 decreases the amount of UCHL1. 4 / 7
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"In the present study, we found that the PGP9.5 increased in sepsis group and MK-801 inhibited the expression of PGP9.5."

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"To further confirm the role of UCH-L1 in breast cancer cell apoptosis, we used MCF7 and Adr derived cells in which over-expression of UCH-L1 was suppressed by transfection of UCH-L1 siRNA."

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"XREF_BIBR Also, it has been demonstrated that ciRS-7 can repress Alzheimer 's disease (AD) development by suppressing NF-kappaB protein synthesis and inducing its cytoplasmic localization, promoting UCHL1 expression and UCHL1 induced amyloid precursor protein (APP) and BACE1 ubiquitination and degradation."

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"By using immunohistochemistry and Western blot study, we observed that the PGP9.5 increased in sepsis group and MK-801 inhibited the expression of PGP9.5 (Figure 3A)."