IndraLab

Statements

CYLD inhibits polyubiquitination. 3 / 4
| 3
sparser
"Importantly, the Lys-63-linked polyubiquitination of transfected Smad7 was effectively inhibited by wild type CYLD, but not by mutant CYLD lacking enzyme activity ( xref C )."
21931165
sparser
"CYLD does not inhibit TAK1/TAB1 co-overexpression-induced TAK1 polyubiquitination."
21331078
sparser
"Conversely, the PB1 domain of p62 also interacts with CYLD, a deubiquitinase, which inhibits TRAF6 polyubiquitination and serves as a negative regulator for RANK-mediated NF-κB activation and osteoclastogenesis xref ."
23856904