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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach

TP53 bound to its increases the amount of CDKN1A. 1 / 1
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"A possible mechanism behind the changes in SWI-SNF composition could be that phosphorylation of TMF-1 by Fer and/or PDGFRbeta promotes disruption of the TMF-1-containing repressive SWI and SNF complex; this may lead to release of Brg-1 followed by its binding to p53, which activates the transcription of CDKN1A, although interaction with the kinase inactive receptor may maintain a repressive SWI and SNF complex and inhibit p21 expression."