IndraLab

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"Several viral NCs can block the IFN signal transfer; lymphocytic choriomeningitis virus (LCMV) NCs can block the IFN signal transfer through interfere the function of IKKε; NCs of Andes virus (ANDV) and porcine epidemic diarrhea virus (PEDV) inhibit IFN signal by interfering with function of TBK1 and IRF3; Arenavirus NCs prevent IRF3 from localizing to nucleus and Borna diseae virus (BDV) NCs prevent IRF7 from localizing to nucleus."